Plasma proteomic profile reveals persistent immune activation in post-acute sequelae of SARS-CoV-2 infection

March 12, 2026 | John Murphy | Leave a Comment

Plasma proteomic profile reveals persistent immune activation in post-acute sequelae of SARS-CoV-2 infection

Abstract Plasma proteomic profiling of 92 individuals with Post-Acute Sequelae of SARS-CoV-2 infection (PASC), assessed a mean of 34 months after acute infection, revealed a distinct inflammatory signature. Using proximity…[...]

March 11, 2026 | John Murphy | Leave a Comment

Comparative efficacy and safety of pharmacological interventions for the treatment of long COVID in adults

Hailu Zhou, Fei Jiang, Zhigang Jiang Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, represents a major global pandemic of the 21st century, with long-term effects termed long COVID. This systematic review and…[...]

March 10, 2026 | John Murphy | Leave a Comment

Long COVID may be triggering Alzheimer’s-like changes in the brain

Tracy Swartz Over 20 million Americans are believed to have the debilitating post-infection condition, suffering symptoms such as severe fatigue, shortness of breath, chest pain, palpitations, dizziness and muscle pain. Now, new research from NYU…[...]

March 9, 2026 | John Murphy | Leave a Comment

Peripheral Nerve Neuropathy in Post‑Acute Sequelae of SARS‑CoV‑2 Infection (PASC)

John Murphy, M.D., M.P.H., D.P.H. Covid-19LOng-haul Foundation Abstract Post‑acute sequelae of SARS‑CoV‑2 infection (PASC), commonly known as long‑COVID, is a multisystem disorder affecting 10–20% of patients following acute infection. Among…[...]

March 8, 2026 | John Murphy | Leave a Comment

Long COVID associated with SARS-CoV-2 reinfection among children and adolescents in the omicron era

Bingyu Zhang, MSa,b ∙ Qiong Wu, PhDa,c,d ∙ Prof Ravi Jhaveri, MDf ∙ et. al. Summary Background Post-acute sequelae of SARS-CoV-2 infection (PASC) remain a major public health challenge. Although previous studies have focused on characterising PASC in children and adolescents after an…[...]

March 7, 2026 | John Murphy | Leave a Comment

Global Prevalence of Long COVID, Its Subtypes, and Risk Factors: An Updated Systematic Review and Meta-analysis Open Access

Yiren Hou , Tian Gu , Zhouchi Ni , et. al. Open Forum Infectious Diseases, Volume 12, Issue 9, September 2025, ofaf533, https://doi.org/10.1093/ofid/ofaf533 Abstract Background This mega-systematic review evaluated the global prevalence of long COVID and…[...]

March 6, 2026 | John Murphy | Leave a Comment

What exactly is Long COVID? New UCLA research shows the answer depends on whom you ask

Lack of a standard definition leads to widely varying estimates, complicating care and research What is Long COVID? Despite hundreds of published studies and millions affected worldwide, the medical field still…[...]

March 5, 2026 | John Murphy | Leave a Comment

Researchers identify viral suspects that could be fueling long COVID

Rutgers University Summary: Scientists are uncovering a new possibility behind long COVID’s stubborn symptoms: hidden infections that awaken or emerge alongside SARS-CoV-2. Evidence is mounting that viruses like Epstein-Barr and…[...]

March 4, 2026 | John Murphy | Leave a Comment

Scientists detect virus traces in blood that may unlock long COVID’s mystery

Scientists have found protein fragments from the COVID-19 virus hidden inside tiny cellular packages in the blood of long COVID patients, offering the first potential measurable biomarker for the condition.…[...]

March 3, 2026 | John Murphy | Leave a Comment

Scientists uncover biological cause of Long COVID brain fog in major breakthrough

By Theo Farrant New research offers what scientists describe as the first biological evidence of Long COVID brain fog. Scientists in Japan have identified a potential biological cause of Long COVID brain fog,…[...]