Long Covid linked to multiple organ changes, research suggests

23/09/2023 The authors of the new study, which was published in The Lancet Respiratory Medicine journal, said it marks a “step forward” in helping long Covid sufferers. The study is the first to look at magnetic resonance imaging (MRI) scans of multiple organs — the brain, heart, liver, kidneys and lungs — after being hospitalised […]

‘Statistically Significant Increase’ In Myopericarditis And Single Organ Cutaneous Vasculitis Found After COVID-19 Vaccination

FRIDAY, SEP 15, 2023 Authored by Megan Redshaw The Epoch Times  A large nationwide study of more than 4 million people in New Zealand identified a statistically significant association in two adverse events following vaccination with Pfizer’s COVID-19 vaccine. In the post-marketing safety study recently published in Springer, researchers examining 12 specific adverse events found an increase […]

Drug-Induced Liver Injury After COVID-19 Vaccine

Authors: Monitoring Editor: Alexander Muacevic and John R AdlerRupinder Mann,1Sommer Sekhon,2 and Sandeep Sekhon3 Cureus. Published onlined doi: 10.7759/cureus.16491 PMCID: PMC8372667PMID: 34430106 Abstract The first case of coronavirus disease 2019 (COVID-19) was reported in December 2019 in China. World Health Organization declared it a pandemic on March 11, 2020. It has caused significant morbidity and mortality worldwide. Persistent symptoms and serious […]

Liver injury after mRNA-based SARS-CoV-2 vaccination in a liver transplant recipient

Authors: Jérôme Dumortiera,b,⁎ Clin Res Hepatol Gastroenterol. 2022 Jan; 46(1):101743.16.  doi: 10.1016/j.clinre.2021.101743 PMCID: PMC8214934PMID: 34146727 Coronavirus disease-2019 (Covid-19) caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is an ongoing global pandemic of major concern, started at the end of 2019. Patients with comorbidities are at high risk of developing severe disease and this includes solid organ transplant recipients [1]. Therefore, […]

How the Pfizer-BioNTech COVID-19 vaccine affects human liver cells

Authors: Lund University MARCH 10, 2022 Medical Xpress A recent study from Lund University in Sweden on how the Pfizer-BioNTech COVID-19 vaccine affects human liver cells under experimental conditions, has been viewed more than 800,000 times in just over a week. The results have been widely discussed across social media—but the results have in many cases […]

Nonintegrating Direct Conversion Using mRNA into Hepatocyte-Like Cells

Authors:: angtae Yoon, 1 , 2 Kyojin Kang, 1 , 2 Young-duck Cho, 3 Yohan Kim, 1 , 2 Elina Maria Buisson, 1 , 2 Ji-Hye Yim, 1 , 2 Seung Bum Lee, 4 Ki-Young Ryu, 5 Jaemin Jeong, 1 , 2 and Dongho Choi 1 , 2 Biomed Res Int. 2018; 2018: 8240567.Published online 2018 Sep 20.doi:  10.1155/2018/8240567 PMCID: PMC6171260PMID: 30327781 Abstract Recently, several researchers have reported that direct reprogramming techniques can be used to differentiate fibroblasts into hepatocyte-like cells without a pluripotent […]

Clinical update on risks and efficacy of anti-SARS-CoV-2 vaccines in patients with autoimmune hepatitis and summary of reports on post-vaccination liver injury

Authors: Ana Lleo 1, Nora Cazzagon 2, Cristina Rigamonti 3, Giuseppe Cabibbo 4, Quirino Lai 5, Luigi Muratori 6, Marco Carbone 7, Italian Association for the Study of the LiverAffiliations expand PMID: 35410851 PMCID: PMC8958090DOI: 10.1016/j.dld.2022.03.014 Published:March 27, 2022DOI:https://doi.org/10.1016/j.dld.2022.03.014 Abstract Patients with liver diseases, especially those with cirrhosis, have an increased mortality risk when infected by SARS-CoV-2 and therefore anti-SARS-CoV-2 vaccine has been recommended by leading Scientific Associations for all patients with chronic […]

A Case of Hepatotoxicity After Receiving a COVID-19 Vaccine

Authors: Muath M. Alqarni, Ammar Z. Faloudah, Amjad S. Alsulaihebi, Hassan K. Halawani, Abdulmajeed S. Khan Published: December 16, 2021  DOI: 10.7759/cureus.20455 Abstract The coronavirus disease 2019 (COVID-19) has led to a global health crisis. Its clinical manifestations are well-documented, and severe complications among patients who survived the infection are being continuously reported. Several vaccines with well-established efficacies and excellent safety […]

Autoimmune hepatitis after SARS-CoV-2 vaccine: New-onset or flare-up?

Authors: Enver Avci 1, Fatma Abasiyanik 2 Autoimmune 2021 Dec;125: 102745. doi: 10.1016/j.jaut.2021.102745  Epub 2021 Nov 11. PMID:  34781161PMCID: PMC8580815DOI: 10.1016/j.jaut.2021.102745 Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been reported to trigger several autoimmune diseases. There are also recent reports of autoimmune diseases that develop after SARS-CoV-2 vaccines. Autoimmune hepatitis is a polygenic multifactorial disease, which is diagnosed […]

Acute hepatitis with autoimmune features after COVID-19 vaccine: coincidence or vaccine-induced phenomenon?

Authors: José M Pinazo-Bandera 1, Alicia Hernández-Albújar 1, Ana Isabel García-Salguero 2,  Isabel Arranz-Salas 2, Raúl J Andrade 1 3, Mercedes Robles-Díaz 1 3 Gastroenterol Rep (Oxf) 2022 Apr 27;10:goac014. doi: 10.1093/gastro/goac014. eCollection 2022. Introduction Autoimmune diseases result from a breach of immunological self-tolerance and tissue damage by autoreactive T lymphocytes. Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection is characterized by an inflammatory dysregulation that has been associated with […]