Doxycycline, a widely used antibiotic in dermatology with a possible anti‐inflammatory action against IL‐6 in COVID‐19 outbreak

Claudio Conforti, 1 Roberta Giuffrida, 2 Iris Zalaudek, 1 and Nicola Di Meo 1 Dermatol Ther. 2020 Jul-Aug; 33(4): e13437. Published online 2020 May 15. doi: 10.1111/dth.13437 PMCID: PMC7235480PMID: 32314492 The recent SARS‐CoV‐2 pandemic, for which there is still no approved vaccine, required research into effective treatments to limit, contain, and improve the outcome of affected patients. 1 , 2 Symptoms of coronavirus disease 19 (COVID‐19) range from mild to severe […]

Severe COVID ‘Rare’ in People Who Didn’t Get Vaccine, Survey Reveals

A survey of 300,000 people who didn’t get the COVID-19 vaccine revealed the unvaccinated didn’t place a disproportionate burden on health systems — in fact, they experienced very low rates of hospitalization and severe COVID-19. Authors: Alliance for Natural Health International 06/09/22 There have been very few studies looking at how those who’ve elected to […]

The Epidemiology, Transmission, and Diagnosis of COVID-19

Authors: By: Neesha C. Siriwardane & Rodney Shackelford, DO, Ph.D. April 15, 2020 Introduction to COVID-19 Coronaviruses are enveloped single-stranded RNA viruses of the Coronaviridae family and order Nidovirales (1). The viruses are named for their “crown” of club-shaped S glycoprotein spikes, which surround the viruses and mediate viral attachment to host cell membranes (1-3). Coronaviruses are found in domestic […]

Prophylaxis against covid-19: living systematic review and network meta-analysis

Authors: Jessica J Bartoszko, methodologist,1 ,*Reed A C Siemieniuk, methodologist, internist,1 ,*Elena Kum, methodologist,1 ,*Anila Qasim, methodologist,1 ,*Dena Zeraatkar, methodologist,1 ,*Long Ge, methodologist,2 ,*Mi Ah Han, methodologist,3Behnam Sadeghirad, assistant professor,1,4Arnav Agarwal, methodologist, internist,1,5Thomas Agoritsas, methodologist, internist,1,6Derek K Chu, methodologist, immunologist,1,7Rachel Couban, librarian,4Andrea J Darzi, methodologist,1Tahira Devji, methodologist,1Maryam Ghadimi, methodologist,1Kimia Honarmand, methodologist, critical care physician,8Ariel Izcovich, methodologist, internist,9Assem Khamis, data analyst,10Francois Lamontagne, methodologist, critical care physician,11Mark Loeb, methodologist, infectious disease physician,1,7Maura Marcucci, methodologist, internist,1,7Shelley L McLeod, methodologist, assistant professor,12,13Sharhzad […]

Critics Fault Henry Ford Hydroxychloroquine Study Methodology, Conclusion

Authors: by Alex McLenon | July 15, 2020 One critic says the study, which found the drug led to fewer COVID-19 deaths, did not used a randomized trial and patients not administered the drug were more likely to die anyway. A recent Henry Ford Health System study finding COVID-19 patients treated with hydroxycloroquine were less likely to die from the virus is drawing skepticism […]

An Update: Is hydroxychloroquine effective for COVID-19?

Authors: Medically reviewed by Last updated on Feb 2, 2021. Multiple studies provide data that hydroxychloroquine (brand name: Plaquenil) does not provide a medical benefit for hospitalized patients with COVID-19. Hydroxychloroquine, an FDA-approved prescription drug used for malaria, rheumatoid arthritis and lupus erythematosus, has been suggested as a possible treatment or preventive for COVID-19 based […]

Treatment with Hydroxychloroquine Cut Death Rate Significantly in COVID-19 Patients, Henry Ford Health System Study Shows

Authors: COVID-19 Media Briefing with Dr. Adnan Munkarah DETROIT – Treatment with hydroxychloroquine cut the death rate significantly in sick patients hospitalized with COVID-19 – and without heart-related side-effects, according to a new study published by Henry Ford Health System. In a large-scale retrospective analysis of 2,541 patients hospitalized between March 10 and May 2, 2020 across the system’s […]

Peer-Reviewed Publications about COVID-19 (Coronavirus) by Yale Authors

Sharing knowledge about COVID-19 (coronavirus) is vital to our efforts as we fight the pandemic. Yale researchers are publishing their discoveries about COVID-19 (coronavirus) in peer-reviewed publications. Check back frequently to access the latest findings. Peer-Reviewed COVID-19 Publications from Yale A new positive SARS-CoV-2 test months after severe COVID-19 illness: reinfection or intermittent viral shedding?Tuan […]

Hydroxychloroquine for the Prevention of Covid-19 — Searching for Evidence

Authors: Myron S. Cohen, M.D. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (Covid-19), has generated a worldwide pandemic. The interruption of its spread depends on a combination of pharmacologic and nonpharmacologic interventions. Initial SARS-CoV-2 prevention includes social distancing, the use of face masks, environmental hygiene, and hand washing.1 Although […]

Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial

Authors: Philippe Gautret 1, Jean-Christophe Lagier 2, Philippe Parola 1, Van Thuan Hoang 3, Line Meddeb 4, Morgane Mailhe 4, Barbara Doudier 4, Johan Courjon 5, Valérie Giordanengo 6, Vera Esteves Vieira 4, Hervé Tissot Dupont 2, Stéphane Honoré 7, Philippe Colson 2, Eric Chabrière 2, Bernard La Scola 2, Jean-Marc Rolain 2, Philippe Brouqui 2, Didier Raoult 8 Abstract Background: Chloroquine and hydroxychloroquine have been found to be efficient on SARS-CoV-2, and reported to be efficient in Chinese COV-19 patients. We evaluate the effect of hydroxychloroquine on respiratory viral loads. […]