Category: Pathology

SARS-CoV-2 infection and persistence in the human body and brain at autopsy

Posted on | Posted on jmurphy | Leave a Comment on SARS-CoV-2 infection and persistence in the human body and brain at autopsy

Authors: by Covid Strategies | Dec 14, 2022 | Science & News Nature Abstract Coronavirus disease 2019 (COVID-19) is known to cause multi-organ dysfunction1,2,3 during acute infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), with some patients experiencing prolonged symptoms, termed post-acute sequelae of SARS-CoV-2 (refs. 4,5). However, the burden of infection outside the respiratory tract and time to viral clearance […]

COVID-19 Autopsies Uncover Ways The Coronavirus Kills April 29, 2021 Angus Chen

Posted on | Posted on jmurphy | Leave a Comment on COVID-19 Autopsies Uncover Ways The Coronavirus Kills April 29, 2021 Angus Chen

When patients become severely ill with COVID-19, the coronavirus infiltrates deep into the lungs and causes mayhem on the tissues that line the organ. The infection can cause swelling, and fluid and debris can start to fill the lungs. It can feel like drowning on dry land. Patients who remember being intubated sometimes describe the […]

Pathophysiology and Management of Tongue Involvement in COVID-19 Patients

Posted on | Posted on jmurphy | Leave a Comment on Pathophysiology and Management of Tongue Involvement in COVID-19 Patients

Authors: Zeinab Mohseni Afshar, Mohammad Barary, Soheil Ebrahimpour, Alireza Janbakhsh, Mandana Afsharian, Amirhossein Hasanpour & Arefeh Babazadeh Indian Journal of Otolaryngology and Head & Neck Surgery (2022) Abstract Evaluate the lingual manifestations of COVID-19, and provide a clinical guide in managing these symptoms. Electronic databases, such as PubMed/Medline, and Scopus were searched until November 1, 2020, and only randomized controlled trials, cross-sectional and cohort […]

‘Never Seen’ Before: Embalmers Finding Long, Rubbery Clots Inside Corpses Since Implementation of Covid Vaccines

Posted on | Posted on jmurphy | Leave a Comment on ‘Never Seen’ Before: Embalmers Finding Long, Rubbery Clots Inside Corpses Since Implementation of Covid Vaccines

By Cristina Laila September 4, 2022 Embalmers are finding long, rubbery clots inside of corpses since the implementation of Covid vaccines. According to one Alabama embalmer who has been treating corpses for over 20 year, the strange fibrous clots emerged in May of 2021, shortly after the Covid vaccines first became available to the public. “It […]

Neuropathology and virus in brain of SARS-CoV-2 infected non-human primates

Posted on | Posted on jmurphy | Leave a Comment on Neuropathology and virus in brain of SARS-CoV-2 infected non-human primates

Authors: Ibolya Rutkai, Meredith G. Mayer, Linh M. Hellmers, Bo Ning, Zhen Huang, Christopher J. Monjure, Carol Coyne, Rachel Silvestri, Nadia Golden, Krystle Hensley, Kristin Chandler, Gabrielle Lehmicke, Gregory J. Bix, Nicholas J. Maness, Kasi Russell-Lodrigue, Tony Y. Hu, Chad J. Roy, Robert V. Blair, Rudolf Bohm, Lara A. Doyle-Meyers, Jay Rappaport & Tracy Fischer  Nature Communications volume 13, Article number: 1745 (2022)  Published: 01 April 2022 Abstract Neurological manifestations are a significant complication of coronavirus disease (COVID-19), but underlying mechanisms aren’t well […]

Skin Manifestations Associated with COVID-19: Current Knowledge and Future Perspectives

Posted on | Posted on jmurphy | Leave a Comment on Skin Manifestations Associated with COVID-19: Current Knowledge and Future Perspectives

Authors: Giovanni Genovese,a,bChiara Moltrasio,a,cEmilio Berti,a,b and Angelo Valerio Marzanoa,b,* Dermatology. 2020 Nov 24 : 1–12.Published online 2020 Nov 24. doi: 10.1159/000512932PMCID: PMC7801998PMID: 33232965 Abstract Background Coronavirus disease-19 (COVID-19) is an ongoing global pandemic caused by the “severe acute respiratory syndrome coronavirus 2” (SARS-CoV-2), which was isolated for the first time in Wuhan (China) in December 2019. Common symptoms include fever, cough, fatigue, […]

First case of postmortem study in a patient vaccinated against SARS-CoV-2

Posted on | Posted on jmurphy | Leave a Comment on First case of postmortem study in a patient vaccinated against SARS-CoV-2

Author:TorstenHansenaUlfTitzeaNidhi Su AnnKulamadayil-HeidenreichbSabineGlombitzacJohannes, et. al. Highlights • We report on a patient with a single dose of vaccine against SARS-CoV-2. • He developed relevant serum titer levels but died 4 weeks later. • By postmortem molecular mapping, we found viral RNA in nearly all organs examined. • However, we did not observe any characteristic morphological features of COVID-19. • […]

Toxic Epidermal Necrolysis Post COVID-19 Vaccination – First Reported Case

Posted on | Posted on jmurphy | Leave a Comment on Toxic Epidermal Necrolysis Post COVID-19 Vaccination – First Reported Case

Authors: Mohamad Bakir, Hanan Almeshal, Rifah Alturki, Sulaiman Obaid, Areej Almazroo Published: August 16, 2021 Abstract Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is a spectrum of acute, delayed-type hypersensitivity reactions that affect the skin and the mucous membranes. Medications are the culprit cause of these disorders in addition to infections and in very rare instances vaccinations. We report a case of […]

Pathological findings in organs and tissues of patients with COVID-19: A systematic review

Posted on | Posted on jmurphy | Leave a Comment on Pathological findings in organs and tissues of patients with COVID-19: A systematic review

Authors: Sasha Peiris 1 2, Hector Mesa 3, Agnes Aysola 4, Juan Manivel 5, Joao Toledo 1 2, Marcio Borges-Sa 6, Sylvain Aldighieri 1 2, Ludovic Reveiz 2 7 Abstract Background: Coronavirus disease (COVID-19) is the pandemic caused by SARS-CoV-2 that has caused more than 2.2 million deaths worldwide. We summarize the reported pathologic findings on biopsy and autopsy in patients with severe/fatal COVID-19 and documented the presence and/or effect of SARS-CoV-2 in all organs. […]

Pathophysiology of COVID-19:

Posted on | Posted on jmurphy | Leave a Comment on Pathophysiology of COVID-19:

Mechanisms Underlying Disease Severity and Progression Authors: Mary Kathryn Bohn,1,2, Alexandra Hall,1 Lusia Sepiashvili,1,2, Benjamin Jung,1,2 Shannon, Steele,1 and Khosrow Adeli1,2,3 The global epidemiology of coronavirus disease 2019 (COVID-19) suggests a wide spectrum of clinical severity, ranging from asymptomatic to fatal. Although the clinical and laboratory characteristics of COVID-19 patients have been well characterized, the […]