How COVID-19 causes neurological damage


Authors: Date:nnNovember 14, 2022 University of Basel Summary:It’s not uncommon for people to lose their sense of taste and smell due to a COVID-19 infection. In others, the disease has had an even stronger impact on the nervous system, with effects ranging from lasting concentration problems to strokes. Now, researchers have reported new insights into […]

COVID-19 inflammation results in urine cytokine elevation and causes COVID-19 associated cystitis (CAC)


Authors: Laura E Lamb 1, Nivedita Dhar 2, Ryan Timar 3, Melissa Wills 3, Sorabh Dhar 4, Michael B Chancellor 5 PMID: 33213997 PMCID: PMC7644255 DOI: 10.1016/j.mehy.2020.110375 Abstract Coronavirus disease 2019 (COVID-19) causes a wide range of symptoms, including several unexpected symptoms such as loss of taste, skin changes, and eye problems. We recently observed patients with documented COVID-19 develop de novo severe genitourinary symptoms, most notably urinary frequency […]

Immunological dysfunction persists for 8 months following initial mild-to-moderate SARS-CoV-2 infection


Authors: Chansavath Phetsouphanh, David R. Darley, Daniel B. Wilson, Annett Howe, C. Mee Ling Munier, Sheila K. Patel, Jennifer A. Juno, Louise M. Burrell, Stephen J. Kent, Gregory J. Dore, Anthony D. Kelleher & Gail V. Matthews  Nature Immunology volume 23, pages210–216 (2022) June 30, 2022 Nature Immunology volume 23, pages210–216 (2022) Abstract A proportion of patients surviving acute coronavirus disease 2019 (COVID-19) infection develop post-acute COVID syndrome (long COVID (LC)) lasting longer […]

New Clues To Long Covid: Prolonged Inflammatory Response


Authors: William A. Haseltine January 2922 Posted July 2022 Forbes For many Covid-19 patients, the end of the acute stage of infection is only the beginning of another difficult experience: Long Covid. Defined by the persistence of physical and neuropsychiatric symptoms over a period of 12 weeks or longer, the exact causes of long Covid […]

Inflammasome activation at the crux of severe COVID-19


Authors: Setu M. Vora,1,2Judy Lieberman,2,3 and Hao Wu1,2 Abstract The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), results in life-threatening disease in a minority of patients, especially elderly people and those with co-morbidities such as obesity and diabetes. Severe disease is characterized by dysregulated cytokine release, pneumonia and acute lung injury, which can […]