Acute blood biomarker profiles predict cognitive deficits 6 and 12 months after COVID-19 hospitalization

Maxime Taquet, Zuzanna Skorniewska, Adam Hampshire, James D. Chalmers, Ling-Pei Ho, Alex Horsley, Michael Marks, Krisnah Poinasamy, Betty Raman, Olivia C. Leavy, Matthew Richardson, Omer Elneima, Hamish J. C. McAuley, Aarti Shikotra, Amisha Singapuri, Marco Sereno, Ruth M. Saunders, Victoria C. Harris, Linzy Houchen-Wolloff, Neil J. Greening, Parisa Mansoori, Ewen M. Harrison, Annemarie B. Docherty, Nazir I. Lone, PHOSP-COVID Study Collaborative Group Nature Medicine (August 2023)  Abstract Post-COVID cognitive deficits, including ‘brain fog’, are clinically complex, with both objective and […]

COVID-19: A Global Threat to the Nervous System

Authors: Igor J. Koralnik MD,Kenneth L. Tyler MD 07 June 2020 Annals of NeurologyVolume 88, Issue 1 p. 1-11 Abstract In less than 6 months, the severe acute respiratory syndrome-coronavirus type 2 (SARS-CoV-2) has spread worldwide infecting nearly 6 million people and killing over 350,000. Initially thought to be restricted to the respiratory system, we now […]

The Impact of Initial COVID-19 Episode Inflammation Among Adults on Mortality Within 12 Months Post-hospital Discharge

Authors: Arch G. Mainous III1,2*, Benjamin J. Rooks1 and Frank A. Orlando1 May 12, 2022 Frontiers in Medicine Background: Inflammation in the initial COVID-19 episode may be associated with post-recovery mortality. The goal of this study was to determine the relationship between systemic inflammation in COVID-19 hospitalized adults and mortality after recovery from COVID-19. Methods: An analysis of electronic health […]

Acute Mesenteric Ischemia in COVID-19 Patients

Authors: Dragos Serban 1,2,*† , Laura Carina Tribus 3,4,†, Geta Vancea 1,5,† , Anca Pantea Stoian, Ana Maria Dascalu 1,* Andra Iulia Suceveanu 6Ciprian Tanasescu 7,8, Andreea Cristina Costea 9 Mihail Silviu Tudosie 1, Corneliu Tudor 2, Gabriel Andrei Gangura 1,10, Lucian Duta 2 and Daniel Ovidiu Costea 6,11, Abstract: Acute mesenteric ischemia is a […]

Review of Mesenteric Ischemia in COVID-19 Patients

Authors: Amit Gupta, Oshin Sharma, Kandhala Srikanth, Rahul Mishra, Amoli Tandon & Deepak Rajput  Indian Journal of Surgery (2022) Published: 11 March 2022 Abstract The new coronavirus (COVID-19) infection, first detected in Wuhan, China in 2019 has become a pandemic that has spread to nearly every country in the world. Through October 11, 2021, more than 23 billion confirmed cases and 4.8 million […]

Characteristics of SARS-CoV-2 and COVID-19

Authors: Ben Hu, Hua Guo, Peng Zhou & Zheng-Li Shi  Nature Reviews Microbiology volume 19, pages141–154 (2021) Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible and pathogenic coronavirus that emerged in late 2019 and has caused a pandemic of acute respiratory disease, named ‘coronavirus disease 2019’ (COVID-19), which threatens human health and public safety. In this Review, we […]

C-Reactive Protein Level May Predict the Risk of COVID-19 Aggravation

Authors: Guyi Wang 1, Chenfang Wu 1, Quan Zhang 2, Fang Wu 3, Bo Yu 1, Jianlei Lv 2, Yiming Li 4, Tiao Li 5, Siye Zhang 1, Chao Wu 6 7 8, Guobao Wu 1, Yanjun Zhong 1Affiliations expand Abstract Background: Clinical findings indicated that a fraction of coronavirus disease 2019 (COVID-19) patients diagnosed as mild early may progress to severe cases. However, it is difficult to distinguish these patients in the early stage. The present study aimed to describe the […]

Elevated level of C‐reactive protein may be an early marker to predict risk for severity of COVID‐19

Authors: Nurshad Ali 1 The outbreak of coronavirus disease‐2019 (COVID‐19) is an emerging global health threat. The healthcare workers are facing challenges in reducing the severity and mortality of COVID‐19 across the world. Severe patients with COVID‐19 are generally treated in the intensive care unit, while mild or non‐severe patients treated in the usual isolation ward […]

The role of C-reactive protein as a prognostic marker in COVID-19

Authors: Dominic Stringer,1Philip Braude,2Phyo K Myint,3Louis Evans,4Jemima T Collins,5Alessia Verduri,6Terry J Quinn,7Arturo Vilches-Moraga,8Michael J Stechman,9Lyndsay Pearce,10Susan Moug,11Kathryn McCarthy,12Jonathan Hewitt,13 and Ben Carter1 Abstract Background C-reactive protein (CRP) is a non-specific acute phase reactant elevated in infection or inflammation. Higher levels indicate more severe infection and have been used as an indicator of COVID-19 disease severity. However, the […]

Can we predict the severe course of COVID-19 – a systematic review and meta-analysis of indicators of clinical outcome?

Authors: Stephan Katzenschlager ,Alexandra J. Zimmer ,Claudius Gottschalk, Jürgen Grafeneder,Stephani Schmitz, Sara Kraker, Marlene Ganslmeier, Amelie Muth, Alexander Seitel, Lena Maier-Hein, Andrea Benedetti, Jan Larmann, Markus A. Weigand, Sean McGrath , Claudia M. Denkinger   Abstract Background COVID-19 has been reported in over 40million people globally with variable clinical outcomes. In this systematic review and meta-analysis, we assessed demographic, […]