Category: Diagnostics

CSF and blood biomarkers in COVID-19 and other neuroinfectious diseases

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Matteo Foschi1,2 Samir Abu-Rumeileh3 Federico Massa4 Christian Cordano4,5 Ahmed Abdelhak5* 11 July 2023 Frontiers in Medicine CSF and blood biomarkers in COVID-19 and other neuroinfectious diseases The past decades have witnessed advances in the development of ultrasensitive assays to measure biofluid markers to improve the diagnosis and characterization of central nervous system (CNS) involvement in primary and non-primary neurological […]

Acute blood biomarker profiles predict cognitive deficits 6 and 12 months after COVID-19 hospitalization

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Maxime Taquet, Zuzanna Skorniewska, Adam Hampshire, James D. Chalmers, Ling-Pei Ho, Alex Horsley, Michael Marks, Krisnah Poinasamy, Betty Raman, Olivia C. Leavy, Matthew Richardson, Omer Elneima, Hamish J. C. McAuley, Aarti Shikotra, Amisha Singapuri, Marco Sereno, Ruth M. Saunders, Victoria C. Harris, Linzy Houchen-Wolloff, Neil J. Greening, Parisa Mansoori, Ewen M. Harrison, Annemarie B. Docherty, Nazir I. Lone, PHOSP-COVID Study Collaborative Group Nature Medicine (August 2023)  Abstract Post-COVID cognitive deficits, including ‘brain fog’, are clinically complex, with both objective and […]

What Is Long COVID?

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By Rachael Zimlich, BSN, RN August 08, 2023 By the end of February 2022, nearly 60% of the U.S. population had SARS-CoV-2 antibodies indicating they had been infected with COVID-19.1 Even for those who recover, SARS-CoV-2 poses serious long-term physical and mental challenges. According to the Centers for Disease Control and Prevention (CDC), around 15% of all adults […]

Changes to Eyes May Signal Long COVID: Study

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Authors:  Marcia Frellick July 28, 2021 British Journal of Ophthalmology Evidence of “long COVID” may be present in a patient’s eyes, according to a small study published online this week in the British Journal of Ophthalmology. The researchers found that nerve fiber loss and an increase in dendritic or key immune cells on the cornea may help identify long […]

First Diagnostic Test for Long Covid, Detecting Spike Protein in Blood, to Launch in September. Or is it ‘Long Vaccine’?

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Authors{ WILL JONES 3 SEPTEMBER 2022  The first diagnostic designed to identify patients with Long Covid has received CE-IVD marking in Europe, meaning it is ready for its formal launch in countries accepting the designation this month. It works by looking for “patterns of inflammatory marker expression” in the blood, and in particular for the […]

Neurotoxic amyloidogenic peptides in the proteome of SARS-COV2: potential implications for neurological symptoms in COVID-19

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Authors : Mirren Charnley, Saba Islam,  Guneet K. Bindra,  Jeremy Engwirda,  Julian Ratcliffe,  Jiangtao Zhou,  Raffaele Mezzenga,  Mark D. Hulett,  Kyunghoon Han,  Joshua T. Berryman & Nicholas P. Reynolds  Nature Communications volume 13, Article number: 3387 (2022)  July 2022 Abstract COVID-19 is primarily known as a respiratory disease caused by SARS-CoV-2. However, neurological symptoms such as memory loss, sensory confusion, severe headaches, and […]

COVID-19: A Global Threat to the Nervous System

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Authors: Igor J. Koralnik MD,Kenneth L. Tyler MD 07 June 2020 Annals of NeurologyVolume 88, Issue 1 p. 1-11 Abstract In less than 6 months, the severe acute respiratory syndrome-coronavirus type 2 (SARS-CoV-2) has spread worldwide infecting nearly 6 million people and killing over 350,000. Initially thought to be restricted to the respiratory system, we now […]

Why are boosted Americans testing positive for COVID more than those without extra shot?

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Authors: Julia Marnin, McClatchy Washington Bureau June 7, 2022 Since late February, Americans who have gotten a booster shot appear to be testing positive for COVID-19 more often than those vaccinated without the extra shot, according to Centers for Disease Control and Prevention data. This is based on numbers up until the week of April […]

The Impact of Initial COVID-19 Episode Inflammation Among Adults on Mortality Within 12 Months Post-hospital Discharge

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Authors: Arch G. Mainous III1,2*, Benjamin J. Rooks1 and Frank A. Orlando1 May 12, 2022 Frontiers in Medicine Background: Inflammation in the initial COVID-19 episode may be associated with post-recovery mortality. The goal of this study was to determine the relationship between systemic inflammation in COVID-19 hospitalized adults and mortality after recovery from COVID-19. Methods: An analysis of electronic health […]

Acute Mesenteric Ischemia in COVID-19 Patients

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Authors: Dragos Serban 1,2,*† , Laura Carina Tribus 3,4,†, Geta Vancea 1,5,† , Anca Pantea Stoian, Ana Maria Dascalu 1,* Andra Iulia Suceveanu 6Ciprian Tanasescu 7,8, Andreea Cristina Costea 9 Mihail Silviu Tudosie 1, Corneliu Tudor 2, Gabriel Andrei Gangura 1,10, Lucian Duta 2 and Daniel Ovidiu Costea 6,11, Abstract: Acute mesenteric ischemia is a […]