Category: Biomarkers

Post-COVID Interstitial Lung Disease—The Tip of the Iceberg

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Namrata Kewalramani, MD,a,b,∗ Kerri-Marie Heenan, MB Bch, BAO,c Denise McKeegan, MB Bch, BAO, MSc,c and Nazia Chaudhuri, MD, PhDd Immunol Allergy Clin North Am. 2023 May; 43(2): 389–410. Published online 2023 Mar3. doi: 10.1016/j.iac.2023.01.004 PMCID: PMC9982726PMID: 37055095 The proportion of symptomatic patients with post-coronavirus 2019 (COVID-19) condition (long COVID) represents a significant burden on the individual as well as on the health care systems. […]

Biomarkers in long COVID-19: A systematic review

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Front. Med., 20 January 2023 Sec. Infectious Diseases: Pathogenesis and TherapyVolume 10 – 2023 | https://doi.org/10.3389/fmed.2023.1085988 Yun-Ju Lai1*† Shou-Hou Liu2† Sumatchara Manachevakul1† Te-An Lee2,3 Chun-Tse Kuo2 Dhimiter Bello4  Purpose: Long COVID, also known as post-acute sequelae of COVID-19, refers to the constellation of long-term symptoms experienced by people suffering persistent symptoms for one or more months after SARS-CoV-2 infection. Blood biomarkers can […]

Biomarkers: Promising and valuable tools towards diagnosis, prognosis and treatment of Covid-19 and other diseases

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Ali Bodaghi,a Nadia Fattahi,b,c and Ali Ramazanib,d,∗ Heliyon. 2023 Feb; 9(2): e13323. Published online 2023 Jan 30. doi: 10.1016/j.heliyon.2023.e13323 PMCID: PMC9884646 PMID: 36744065 The use of biomarkers as early warning systems in the evaluation of disease risk has increased markedly in the last decade. Biomarkers are indicators of typical biological processes, pathogenic processes, or pharmacological reactions to therapy. The application and identification of biomarkers […]

Auditory Disturbances and SARS-CoV-2 Infection: Brain Inflammation or Cochlear Affection? Systematic Review and Discussion of Potential Pathogenesis

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Pietro De Luca1, Alfonso Scarpa1, Massimo Ralli2, Domenico Tassone3, Matteo Simone3, Luca De Campora3, Claudia Cassandro4† and Arianna Di Stadio Frontiers in Medicine Patients affected by COVID-19 present a series of different symptoms; despite some of these are common, other less likely appear. Auditory symptoms seem to be less frequent, maybe because rarer or, alternatively, because they are underestimated during the clinical investigation. […]

Researchers are working together to better understand and treat the syndrome

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Authors:  SABRINA RICHARDS / FRED HUTCH NEWS SERVICE JANUARY 26, 2022 Robin Macnofsky’s first symptoms, in April 2020, were so mild she didn’t take a test for COVID-19, preferring to save it for someone who really needed it. A few weeks later her chest tightened and her temperature spiked. These ebbed, but an even stronger wave […]

Prognostic value of serum/plasma neurofilament light chain for COVID-19-associated mortality

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Authors: Ruturaj R. Masvekar,Peter Kosa,Kimberly Jin,Kerry Dobbs,Michael A. Stack,Riccardo Castagnoli,Virginia Quaresima,Helen C. Su,Luisa Imberti,Luigi D. Notarangelo,Bibiana Bielekova 21 March 2022 Annals of Clinical and Translational Neurology Volume 9, Issue 5 p. 622-632 Abstract Objective Given the continued spread of coronavirus 2, the early predictors of coronavirus disease 19 (COVID-19) associated mortality might improve patients’ outcomes. Increased […]

Laboratory Biomarkers for Diagnosis and Prognosis in COVID-19

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Authors: Denise Battaglini, 1 , 2 , 3 Miquéias Lopes-Pacheco, 4 Hugo C. Castro-Faria-Neto, 5 Paolo Pelosi, 1 , 2 and Patricia R. M. Rocco 4 , 6 , 7 , * Front Immunol. 2022; 13: 857573.  Apr 27.  2022 doi: 10.3389/fimmu.2022.857573 PMCID: PMC9091347 PMID: 35572561 Abstract Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) causes a wide spectrum of clinical manifestations, with progression to multiorgan failure in the most severe cases. Several biomarkers can be altered […]